This is from The Nanny, but I don’t know the episode. Those are the two main characters, though Fran is in a blond wig for some reason. It was made in the 90s and not in black and white, so this must have been a strange episode.

Oh! I found it, or at least this clip: https://youtu.be/82NuUC8WBko

And you stuck to the main, very large highways instead of trying the smaller routes. I always wonder if the Waze era of travel has helped or hurt smaller communities.