Blazing Saddles. It killed the western genre for a long time because of how well it parodied them
Pretty much everything from Weird Al.
For my wife Spaceballs is the original and Star Wars is the spoof.
But more seriously, too many people didn’t register that Scream was a parody. That way it managed to surpass older slashers.
I wouldn’t call Scream a parody. Scary Movie was the parody. Scream was just self aware that it was a scary movie in a universe where scary movies exist.
Hot Fuzz is the best buddy cop movie I’ve ever seen.
Just as Shaun of the Dead is the best zombie movie (come fight me)
Deadpool It was a parody of DCs Deathstroke, right down to the guy’s name Slade/Wade.
While that’s true, it took a few writers before he really came into his own. It was the 2000s before he was the meta, witty, merc with a mouth. The parody was a lot more on the nose and it traded some of the parody for the meta, witty Wheaton-isms and pop culture references. Parody Deadpool and Deadpool Deadpool are arguably different characters.
The best parodies are humorous takes that treat the source material with repect.
Shaun of the Dead
Galaxy Quest
Army of Darkness (person out of time becomes a leader against evil)
Galaxy Quest belongs at the top of any such list. It’s widely considered to be one of the best Star Trek movies.
By Grabthar’s hammer, what a movie.
WHAT’S MY LAST NAME??!?
…Maybe I’m the plucky comic relief…
“Let’s get out of here before one of those things kills Guy” is still low-key one of my favourite lines.